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Bespoke Projects

Modern healthcare systems produce endless amounts of data, but finding the right data to enhance your organization’s research and development activity can be a challenge.

 

At NashBio, our Bespoke Project solutions make complex healthcare data easy to use. Our approach focuses on your use case – tailoring a multimodal dataset to your unique specifications to achieve an optimal return on your clinical, operational and financial investment.

NashBio’s Bespoke solutions are trusted by organizations worldwide. See what some of our clients have to say about working with us.

Patient Demographics

4M

 

patients

4.1 years

 

median length of patient EHR

6 visits

 

median per patient

EHR-Reported Race

EHR-Reported Gender

Age at Last EHR

Smarter Data That Enables Deeper Analysis and Discovery

Large-scale association analyses are commonly performed to link phenotypic and genomic datasets. Study findings may elucidate new targets for drug discovery or new patient populations that would benefit from repurposing an existing therapeutic. Nashville Biosciences’ 90,000-subject MEGAEX + linked de-identified electronic health records dataset serves as the substrate for our association studies.

GWAS & PheWAS Studies

Genome-wide association studies (GWAS)

Nashville Biosciences works with our customers to define appropriate case and control cohorts, balancing cohort refinement with adequate sample size. A GWAS package includes a statistical output file (e.g., P-values, odds ratio, variant), Manhattan plots and Q-Q plots.

Phenome-wide association studies (PheWAS)

Nashville Biosciences can deliver precomputed PheWAS data from the entire dataset or perform a custom PheWAS analysis based on the genes and variants of interest to our customers. A PheWAS package includes a statistical output file (e.g., P-values, odds ratio, variant) and Manhattan plots.

Our clients and partners include many of the world’s leading health care organizations:

Use Cases

Our use cases demonstrate how our data, expertise, and insights can improve the success rates of clinical research to accelerate scientific discoveries. 

Identifying novel drug targets for pain relief using genomics and real-world data

 

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Improving AI-guided clinical decision support with enriched data and industry expertise

 

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Developing predictive diagnosis algorithms using electronic health records

 

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Case Studies

These case studies illustrate how we leverage our expansive dataset and expertise to develop innovative solutions for our clients.

Disease Risk Modeling

Acute pancreatitis has become increasingly prevalent across the world, affecting nearly 85,000 individuals annually. Patients with acute pancreatitis experience significant rates of mortality in the emergency department…

 

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Molecular Data Generation

Improving Early-Stage Drug Discovery Process. We worked with Pfizer’s Target Sciences and Technologies group to explore genetic targets for treating a serious metabolic disease with greatly increasing prevalence…

 

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Genetic Data Retrieval Tool

Assessing pain-associated SNPs through the linkage of genetic and clinical information. Hereditary neuropathies are a group of peripheral nervous system disorders that are characterized by numbness…

 

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