Diabetic nephropathy (DN), a chronic condition that occurs in patients with diabetes mellitus, is a major factor chronic kidney disease and end-stage renal failure. Given the increasing prevalence of type 2 diabetes (T2D) coupled with the fact that DN occurs in 25% of T2D adults, the condition has become the biggest cause of end-stage renal disease and requires additional investigation in order to develop novel therapeutics designed to combat the disease.