This collection of case studies highlights how NashBio leverages a multimodal clinico-genomic dataset, integrating Whole Genome Sequencing (WGS), longitudinal EHR data, and time-indexed cardiac imaging to advance cardiovascular research. From resolving phenotypic heterogeneity in hereditary cardiomyopathy and heart failure (HFrEF vs. HFpEF) to exploring precision lipidology and cardiovascular pleiotropy, these studies demonstrate a data-driven approach to identifying novel targets and enabling precise patient stratification. Discover how high-depth clinical insights and advanced NLP are transforming reactive symptom management into proactive, genotype-informed care.